原著論文(英文)

研究業績(2020年)

2020

  • Ichikawa R, Kawasaki R, Iwata A, Otani S, Nishio E, Nomura H, Fujii T. MicroRNA- 126-3p suppresses HeLa cell proliferation, migration and invasion, and increases apoptosis via the PI3K/PDK1/AKT pathway. Oncol Rep, 43:1300-1308, 2020
  • Ando Y, Hayashi T, Shiouchi H, Tanaka C, Ito K, Nishibe S, Miyata N, Horiba R, Yanagi H, Fujii T, Kawada K, Ikeda Y, Yamada S. Effect of obesity on hematotoxicity induced by carboplatin and paclitaxel combination therapy in patients with gynecological cancer. Biol Pharm Bull. 43(4):669-674, 2020
  • Fukushima H, Fujii T, Sugiura K. Zinc-responsive necrolytic acral erythema in ovarian cancer. J Dermatol. 47(7):e266-e267, 2020
  • Nishio E, Hayashi T, Akaza M, Hisatomi Y, Hikichi M, Fujii T, Utsumi T, Harada N, Shimono Y. Upregulation of CIP2A in estrogen depletion-resistant breast cancer cells treated with low-dose everolimus. FEBS Open Bio. 10(10):2072-2080, 2020
  • Ohwaki A, Nishizawa H, Kato A, Kato T, Miyazaki J, Yoshizawa H, Noda Y, Sakabe Y, Ichikawa R, Sekiya T, Fujii T, Kurahashi H. Placental genetic variants in the upstream region of the FLT1 gene in pre-eclampsia. J Reprod Infertil. 21(4):240-246, 2020
  • Komatsu H, Banno K, Yanaihara N, Kimura T, Board Members of Japan Society of Obstetrics and Gynecology: Aoki D, Kato K, Ikeda T, Osuga Y, Okamoto A, Mandai M, Yaegashi N, Mikami M, Kudo Y, Sekizawa A, Enomoto T, Kamei Y, Kobayashi Y, Koyama M, Sameshima H, Shibahara H, Shozu M, Sugino N, Takeshita T, Nagase S, Fujii T, Maeda N, Miyamoto S, Watari H. Prevention and practice during the COVID-19 emergency declaration period in Japanese obstetrical-gynecological facilities. J Obstet Gynaecol Res. 46(11):2237-2241, 2020
  • Kawahara R, Fujii T, Kukimoto I, Nomura H, Kawasaki R, Nishio E, Ichikawa R, Tsukamoto T, Iwata A. Changes to the cervicovaginal microbiota and cervical cytokine profile following surgery for cervical intraepithelial neoplasia. Sci Rep. 11(1):2156, 2021
  • Tamauchi S, Kajiyama H, Osuka S, Moriyama Y, Yoshihara M, Kikkawa F. “Reduced response to controlled ovarian stimulation after radical trachelectomy: A pitfall of fertility-sparing surgery for cervical cancer. Int J Gynaecol Obstet. doi: 10.1002/ijgo.13529. Online ahead of print. 2021
  • Nakamura N, Ushida T, Nakatochi M, Kobayashi Y, Moriyama Y, Imai K, Nakano-Kobayashi T, Hayakawa M, Kajiyama H, Kikkawa F, Kotani T; Neonatal Research Network of Japan. Mortality and neurological outcomes in extremely and very preterm infants born to mothers with hypertensive disorders of pregnancy. Sci Rep. 11(1):1729, 2021
  • Ito Y, Tsuda H, Imai K, Miki R, Miura M, Tachi A, Tano S, Hirako-Takamura S, Moriyama Y, Ushida T, Kobayashi T, Sumigama S, Kajiyama H, Kikkawa F, Kotani T. Vitamin D improves pulmonary function in a rat model for congenital diaphragmatic hernia. Arch Biochem Biophys. 700:108769, 2021.
  • Ushida T, Kotani T, Imai K, Nakano-Kobayashi T, Nakamura N, Moriyama Y, Yoshida S, Yamashita M, Kajiyama H, Kikkawa F. Shock Index and Postpartum Hemorrhage in Vaginal Deliveries: A Multicenter Retrospective Study. Shock.  55(3):332-337, 2021
  • Ushida T, Kotani T, Kinoshita F, Imai K, Nakano-Kobayashi T, Nakamura N, Moriyama Y, Yoshida S, Yamashita M, Kajiyama H. Maternal low birth weight and hypertensive disorders of pregnancy. Pregnancy Hypertens. 23:5-10, 2021.
  • Ushida T, Kotani T, Kinoshita F, Imai K, Nakano-Kobayashi T, Nakamura N, Moriyama Y, Yoshida S, Yamashita M, Kajiyama H. Liver transaminase levels during pregnancy: a Japanese multicenter study. J Matern Fetal Neonatal Med. 28;1-7, 2021
  • Ushida T, Moriyama Y, Nakatochi M, Kobayashi Y, Imai K, Nakano-Kobayashi T, Nakamura N, Hayakawa M, Kajiyama H, Kotani T; Neonatal Research Network of Japan. Antenatal prediction models for short- and medium-term outcomes in preterm infants. Acta Obstet Gynecol Scand. 2021 (in press)
  • Ushida T, Kotani T, Moriyama Y, Hindmarch CCT, Cotechini T, Imai K, Nakano-Kobayashi T, Kajiyama H, Graham CH. Postpartum alterations following inflammation in rat pregnancy: a discovery proteomic analysis. Reproduction. 2021 (in press)
  • Mitamura T, Sekine M, Arai M, Shibata Y, Kato M, Yokoyama S, Yamashita H, Watari H, Yabe I, Nomura H, Enomoto T, Nakamura S, the Registration Committee of the Japanese HBOC consortium. The disease sites of female genital cancers of BRCA1/2-associated hereditary breast and ovarian cancer: a retrospective study. World J Surg Oncol. 19(1):36, 2021
  • Nanki Y, Nomura H, Iwasa N, Saotome K, Dozen A, Yoshihama T, Hirano T, Hashimoto S, Chiyoda T, Yamagami W, Kataoka F, Aoki D. A prospective cohort study on the safety and efficacy of bevacizumab combined with chemotherapy in Japanese patients with relapsed ovarian, fallopian tube, or primary peritoneal cancer. Jpn J Clin Oncol. 51(1):54-59, 2021
  • Sakai K, Nakamura M, Yamagami W, Chiyoda T, Kobayashi Y, Nishio H, Hayashi S, Nomura H, Kataoka F, Tominaga E, BannoK, Aoki D. Evaluating the importance of routine drainage following laparoscopic pelvic lymph node dissection for gynecological malignancies. Int J Gynaecol Obstet. 2020 (in press)
  • Saotome K, Chiyoda T, Aimono E, Nakamura K, Tanishima S, Nohara S, Okada C, Hayashi H, Kuroda Y, Nomura H, Susumu N, Iwata T, Yamagami W, Kataoka F, Nishihara H, Aoki D. Clinical implications of next generation sequencing-based panel tests for malignant ovarian tumors. Cancer Med. 9(20):7407-7417, 2020
  • Mitamura T, Sekine M, Arai M, Shibata Y, Kato M, Yokoyama S, Yamashita H, Watari H, Yabe I, Nomura H, Enomoto T, Nakamura S, the Registration Committee of the Japanese HBOC Consortium. Risk factors for lymph node metastasis of ovarian, fallopian tube and primary peritoneal cancer in hereditary breast and ovarian cancer syndrome. Jpn J Clin Oncol. 16;50(12):1380-1385, 2020

研究業績(2016年～2019年)

  • Ichikawa R, Kawasaki R, Iwata A, Otani S, Nishio E, Nomura H, Fujii T. MicroRNA 126 3p suppresses HeLa cell proliferation, migration and invasion, and increases apoptosis via the PI3K/PDK1/AKT pathway. Oncol Rep, 43:1300-1308, 2020
  • Nomura H, Aoki D, Susumu N, Mizuno M, Nakai H, Arai M, Nishio S, Tokunaga H, Nakanishi T, Watanabe Y, Yaegashi N, Yokoyama Y, Takehara K. Analysis of the relapse patterns and risk factors of endometrial cancer following postoperative adjuvant chemotherapy in a phase III randomized clinical trial. Gynecol Oncol. 155:413-419, 2019
  • Nishio E, Hayashi T, Nakatani M, Aida N, Suda R, Fujii T, Wakatsuki T, Honda S, Harada N, Shimono Y. Lack of association of ovariectomy-induced obesity with overeating and the reduction of physical activities. Biochem Biophys Rep. 20:100671, 2019
  • Otani S, Fujii T, Kukimoto I, Yamamoto N, Tsukamoto T, Ichikawa R, Nishio E, Iwata A. Cytokine expression profiles in cervical mucus from patients with cervical cancer and its precursor lesions. Cytokine, 120:210-219, 2019
  • Nishio E, Hayashi T, Nakatani M, Aida N, Suda R, Fujii T, Wakatsuki T, Honda S, Harada N, Shimono Y. Lack of association of ovariectomy-induced obesity with overeating and the reduction of physical activities. Biochem Biophys Rep. 20:100671, 2019
  • Noda Y, Kato T, Kato A, Nishizawa H, Miyazaki J, Ito M, Terasawa S, Sekiya T, Fujii T, Kurahashi H. Potentially effective method for fetal gender determination by non-invasive prenatal testing for X-linked disease. Congenit Anom. 59(3):88-92, 2019
  • Kawai S, Torii Y, Kukimoto I, Fujii T. A case of primary signet-ring cell carcinoma of the cervix containing full genome of human papillomavirus 16. Indian J Pathol Microbiol, 62(1): 146-8, 2019
  • Yoshizawa H, Kawai S, Hirota Y, Ueda T, Kuroda M, Fujii T. A case of uterine lymphangioleiomyomatosis in a young woman that was identified via peritonitis. J Obstet Gynaecol Res. 45(2):482-486, 2019
  • Suzumori N, Sekizawa A, Takeda E, Samura O, Sasaki A, Akaishi R, Wada S, Hamanoue H, Hirahara F, Kuriki H, Sawai H, Nakamura H, Yamada T, Miura K, Masuzaki H, Yamashita T, Kamei Y, Namba A, Murotsuki J, Tanemoto T, Fukushima A, Haino K, Tairaku S, Matsubara K, Maeda K, Kaji T, Ogawa M, Osada H, Nishizawa H, Okamoto Y, Kanagawa T, Kakigano A, Endo M, Kitagawa M, Ogawa M, Izumi S, Katagiri Y, Takeshita N, Kasai Y, Naruse K, Neki R, Masuyama H, Hyodo M, Kawano Y, Ohba T, Ichizuka K, Nagamatsu T, Watanabe A, Nishikawa N, Hamajima N, Shirato N, Yotsumoto J, Nishiyama M, Koide K, Hirose T, Sago H. Classification of factors involved in nonreportable results of noninvasive prenatal testing (NIPT) and prediction of success rate of second NIPT. Prenat Diagn. 39(2):100-106, 2019
  • Terasawa S, Kato A, Nishizawa H, Kato T, Yoshizawa H, Noda Y, Miyazaki J, Ito M, Sekiya T, Fujii T, Kurahashi H. Multiplex PCR in noninvasive prenatal diagnosis for FGFR3-related disorders. Congenit Anom. 59(1):4-10, 2019
  • Ohwaki A, Nishizawa H, Aida N, Kato T, Kambayashi A, Miyazaki J, Ito M, Urano M, Kiriyama Y, Kuroda M, Nakayama M, Sonta SI, Suzumori K, Sekiya T, Kurahashi H, Fujii T. Twin pregnancy with chromosomal abnormalities mimicking a gestational trophoblastic disorder and coexistent foetus on ultrasound. J Obstet Gynaecol. 38(7):1023-1025, 2018.
  • Hayashi T, Hikichi M, Yukitake J, Wakatsuki T, Nishio E, Utsumi T, Harada N. Forskolin increases the effect of everolimus on aromatase inhibitor-resistant breast cancer cells. Oncotarget. 9(34):23451-23461, 2018.
  • Matoda M, Takeshima N, Michimae H, Iwata T, Yokota H, Torii Y, Yamamoto Y, Takehara K, Nishio S, Takano H, Mizuno M, Takahashi Y, Takei Y, Hasegawa T, Mikami M, Enomoto T, Aoki D, Sugiyama T. Postoperative chemotherapy for node-positive cervical cancer: Results of a multicenter phase II trial (JGOG1067). Gynecol Oncol. 149 (3): 513-519, 2018
  • Kawai S, Fujii T, Kukimoto I, Yamada H, Yamamoto N, Kuroda M, Otani S, Ichikawa R, Nishio E, Torii Y, Iwata A: Identification of miRNAs in cervical mucus as a novel diagnostic marker for cervical neoplasia. Sci Rep. 8(1): 7070, 2018
  • Ito M, Nishizawa H, Tsutsumi M, Kato A, Sakabe Y, Noda Y, Ohwaki A, Miyazaki J, Kato T, Shiogama K, Sekiya T, Kurahashi H, Fujii T. Potential role for nectin-4 in the pathogenesis of pre-eclampsia: a molecular genetic study. BMC Med Genet. 19(1):166, 2018
  • Suzumori N, Sekizawa A, Ebara T, Samura O, Sasaki A, Akaishi R, Wada S, Hamanoue H, Hirahara F, Izumi H, Sawai H, Nakamura H, Yamada T, Miura K, Masuzaki H, Yamashita T, Okai T, Kamei Y, Namba A, Murotsuki J, Tanemoto T, Fukushima A, Haino K, Tairaku S, Matsubara K, Maeda K, Kaji T, Ogawa M, Osada H, Nishizawa H, Okamoto Y, Kanagawa T, Kakigano A, Kitagawa M, Ogawa M, Izumi S, Katagiri Y, Takeshita N, Kasai Y, Naruse K, Neki R, Masuyama H, Hyodo M, Kawano Y, Ohba T, Ichizuka K, Nagamatsu T, Watanabe A, Shirato N, Yotsumoto J, Nishiyama M, Hirose T, Sago H. Fetal cell-free DNA fraction in maternal plasma for the prediction of hypertensive disorders of pregnancy. Eur J Obstet Gynecol Reprod Biol. 224:165-169, 2018
  • Ohwaki A, Nishizawa H, Aida N, Kato T, Kambayashi A, Miyazaki J, Ito M, Urano M, Kiriyama Y, Kuroda M, Nakayama M, Sonta S, Suzumori K, Sekiya T, Kurahashi H, Fujii T. Twin Pregnancy with chromosomal abnormalities mimicking a gestational trophoblastic disorder and coexistent foetus on ultrasound. J Obstet Gynaecol. 9:1-3, 2018
  • Ishioka S, Kim M, Mizugaki Y, Kon S, Isoyama K, Mizuuchi M, Morishita M, Baba T, Sekiya T. Transabdominal cerclage (TAC) for patients with ultra-short uterine cervix after uterine cervix surgery and its impact on pregnancy. J Obstet Gynaecol Res. 44(1): 61-66, 2018
  • Samura O, Sekizawa A, Suzumori N, Sasaki A, Wada S, Hamanoue H, Hirahara F, Sawai H, Nakamura H, Yamada T, Miura K, Masuzaki H, Nakayama S, Okai T, Kamei Y, Namba, A, Murotsuki J, Hanemoto T, Fukushima A, Haino K, Tairaku S, Matsubara K, Maeda K, Kaji T, Ogawa M, Osada H, Nishizawa H, Okamoto Y, Kanagawa T, Kakigano A, Kitagawa M, Ogawa M, Izumi S, Katagiri Y, Takeshita N, Kasai Y, Naruse K, Neki R, Masuyama H, Hyodo M, Kawano Y, Ohba T, Ichizuka K, Kido Y, Fukao T, Miharu N, NagamatsuT, Watanabe A, Hamajima N, Hirose M, Sanui A, Shirato N, Yotsumoto J, Nishiyama M, Hirose T, Sago H. Current status of non-invasive prenatal testing in Japan. J Obstet Gynaecol Res. 43(8):1245-1255, 2017
  • Nishio E, Kawai S, Akita E, Fujii T. Successful fertility-sparing surgery and chemotherapy for stage Ⅰc3 ovarian cancer with the postoperative use of the traditional Japanese herbal formulation hachimijiogan:a case report. Traditonal & Kampo medicine. 4:124-126, 2017
  • Torii Y, Fujii T, Kukimoto I, Saito M, Iwata T, Takahashi H, Ichikawa R, Kawai S, Otani S, Aoki D. Comparison of methods using paraffin-embedded tissues and exfoliated cervical cells to evaluate human papillomavirus genotype attribution. Cancer Sci. 107(10):1520-1526, 2016
  • Miyazaki J, Nishizawa H, Kambayashi A, Ito M, Noda Y, Terasawa S, Kato T, Miyamura H, Shiogama K, Sekiya T, Kurahashi H, Fujii T. Increased levels of soluble corin in pre-eclampsia and fetal growth restriction. Placenta. 48:20-25 2016
  • Kawai S, Ichikawa R, Ueda T, Urano M, Kuroda M, Fujii T. Ovarian clear cell adenocarcinoma revealed in a young patient during hormone therapy: a case report. Fujita Medical Journal. 2(4): 77-79, 2016
  • Ueda T, Murayama K, Nishizawa H, Fujii T, Toyama H. Preoperative magnetic resonance imaging findings of myoma as risk factors for bleeding during laparoscopic myomectomy. Fujita Medical Journal. 2(3):59-61, 2016
  • Takaiso N, Nishizawa H, Nishiyama S, Sawada T, Hosoba E, Ohye T, Sato T, Inagaki H, Kurahashi H. Mutation analysis of the JUNO gene in female infertility of unknown etiology. Fujita Medical Journal. 2(3): 59-61, 2016
  • Suzumori N, Ebara T; Japan NIPT consortium (Nishizawa H). Fetal cell-free DNA fraction in maternal plasma is affected by fetal trisomy. J Hum Genet. 61(7):647-52, 2016
  • Yotsumoto J, Sekizawa A, Suzumori N, Yamada T, Samura O, Nishiyama M, Miura K, Sawai H, Murotsuki J, Kitagawa M, Kamei Y, Masuzaki H, Hirahara F, Endo T, Fukushima A, Namba A, Osada H, Kasai Y, Watanabe A, Katagiri Y, Takeshita N, Ogawa M, Okai T, Izumi S, Hamanoue H, Inuzuka M, Haino K, Hamajima N, Nishizawa H, Okamoto Y, Nakamura H, Kanegawa T, Yoshimatsu J, Tairaku S, Naruse K, Masuyama H, Hyodo M, Kaji T, Maeda K, Matsubara K, Ogawa M, Yoshizato T, Ohba T, Kawano Y, Sago H and Japan NIPT Consortium. A survey on awareness of genetic counseling for non-invasive prenatal testing: the first year experience in Japan. J Hum Genet 61(12):995-1001, 2016
  • Fujii T. Changing state of gynecologic oncologist specialty in Japan. J Obstet Gynaecol Res. 42(5):481-488, 2016
  • Kasuga Y, Nishio H, Miyakoshi K, Sato S, Sugiyama J, Matsumoto T, Tanaka K, Ochiai D, Minegishi K, Hamatani T, Iwata T, Morisada T, Nakamura M, Fujii T, Kuji N, Aoki D, Tanaka M. Pregnancy Outcomes After Abdominal Radical Trachelectomy for Early-Stage Cervical Cancer: A 13-Year Experience in a Single Tertiary-Care Center. Int J Gynecol Cancer. 26(1):163-8, 2016.

EDUCATION研究・教育

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